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Agomelatine

Agomelatine

Product Details:

  • Chemical Name Phenylephrine
  • CAS No 61-76-7
  • Type Other
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Agomelatine Product Specifications

  • 61-76-7
  • Phenylephrine
  • Other

Agomelatine Trade Information

  • Nhava Sheva / Hazira
  • 2-3 Week
  • Yes
  • Free samples available with shipping and taxes paid by the buyer
  • 25 Kg HDPE Drum
  • All India
  • WHO, GMP, COA, As Per Clients Requirement

Product Description

Agomelatine is an extremely potent agonist at both melatonin receptors (MT1 and MT2), with additional antagonism at 5HT2C. It is a novel antidepressant with many desired in vivo properties, including neuroprotection and neurogenesis in depression-sensitive brain areas.

Agomelatines efficacy appears to be due to both melatonergic and serotonergic properties. In neurogenesis assays, both in vitro and in vivo, the compound effects were differentially affected by antagonists for MT1/MT2 and 5HT2C, demonstrating actions through all three receptors.

  • Formula -C15H17NO2
  • Molar mass -243.301 g/mol
  • Bioavailability -1%
  • Protein binding -95%
  • Metabolism -hepatic (90% CYP1A2 and 10% CYP2C9)
  • Biological half-life - 1-2 hours Excretion -Renal (80%, mostly as metabolites)

Additional Information

The most common markets for this product include the following countries. Please inquire with us if your country or region is not listed:

Asia: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, etc.

Africa: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , etc.

North & South America: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, etc .

Europe: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, etc.

OCEANIA: Australia, New Zealand, Fiji, etc.

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